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1

Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor

Beth A.A. Weaver, Alain D. Silk, Cristina Montagna, Pascal Verdier-Pinard, Don W. Cleveland

Journal:

Year:

2007

Language:

english

File:

PDF, 1.92 MB

english, 2007

2

ChemInform Abstract: Antitumor Agents. Part 172. Synthesis and Biological Evaluation of Novel Deacetamidothiocolchicin-7-ols and Ester Analogues as Antitubulin Agents.

Q. SHI, P. VERDIER-PINARD, A. BROSSI, E. HAMEL, A. T. MCPHAIL, K.-H. LEE

Journal:

Year:

1997

Language:

english

File:

PDF, 31 KB

english, 1997

3

ChemInform Abstract: Antitumor Agents. Part 184. Syntheses and Antitubulin Activity of Compounds Derived from Reaction of Thiocolchicone with Amines: Lactams, Alcohols, and Ester Analogues of Allothiocolchicinoids.

Q. SHI, K. CHEN, A. BROSSI, P. VERDIER-PINARD, E. HAMEL, A. T. MCPHAIL, K.-H. LEE

Journal:

Year:

1998

File:

PDF, 32 KB

1998

4

ChemInform Abstract: Antitumor Agents. Part 183. Syntheses, Conformational Analyses, and Antitubulin Activity of Allothiocolchicinoids.

Q. SHI, K. CHEN, X. CHEN, A. BROSSI, P. VERDIER-PINARD, E. HAMEL, A. T. MCPHAIL, A. TROPSHA, K.-H. LEE

Journal:

Year:

1998

File:

PDF, 32 KB

1998

5

ChemInform Abstract: Curacin D, an Antimitotic Agent from the Marine Cyanobacterium Lyngbya majuscula.

Brian Marquez, Pascal Verdier-Pinard, Ernest Hamel, William H. Gerwick

Journal:

Year:

1999

File:

PDF, 27 KB

1999

6

ChemInform Abstract: Antitumor Agents. Part 192. Antitubulin Effect and Cytotoxicity of C(7)-Oxygenated Allocolchicinoids.

Jian Guan, Xiao-Kang Zhu, Arnold Brossi, Yoko Tachibana, Kenneth F. Bastow, Pascal Verdier-Pinard, Ernest Hamel, Andrew T. McPhail, Kuo-Hsiung Lee

Journal:

Year:

1999

File:

PDF, 32 KB

1999

7

ChemInform Abstract: Convergent Synthesis and Preliminary Biological Evaluation of (.+-.)-B-Norrhazinal.

Martin Banwell, Alison Edwards, Jason Smith, Ernest Hamel, Pascal Verdier-Pinard

Journal:

Year:

2000

File:

PDF, 31 KB

2000

8

ChemInform Abstract: A Novel Palladium-Mediated Coupling Approach to 2,3-Disubstituted Benzo[b]thiophenes and Its Application to the Synthesis of Tubulin Binding Agents.

Bernard L. Flynn, Pascal Verdier-Pinard, Ernest Hamel

Journal:

Year:

2001

File:

PDF, 30 KB

2001

9

Total Synthesis of (.+-.)-Rhazinal, an Alkaloidal Spindle Toxin from Kopsia teoi.

Martin G. Banwell, Alison J. Edwards, Katrina A. Jolliffe, Jason A. Smith, Ernest Hamel, Pascal Verdier-Pinard

Journal:

Year:

2003

File:

PDF, 6 KB

2003

10

Antitumor Agents. Part 184. Syntheses and antitubulin activity of compounds derived from reaction of thiocolchicone with amines: Lactams, alcohols, and ester analogs of allothiocolchicinoids

Qian Shi, Ke Chen, Arnold Brossi, Pascal Verdier-Pinard, Ernest Hamel, Andrew T. McPhail, Kuo-Hsiung Lee

Journal:

Helvetica Chimica Acta

Year:

1998

Language:

english

File:

PDF, 874 KB

english, 1998

11

4,5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: Synthesis and evaluation as anti-mitotic and cytotoxic agents

Martin G. Banwell, Ernest Hamel, David C.R. Hockless, Pascal Verdier-Pinard, Anthony C. Willis, David J. Wong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 390 KB

english, 2006

12

Tubulin proteomics: Towards breaking the code

Pascal Verdier-Pinard, Eddy Pasquier, Hui Xiao, Berta Burd, Claude Villard, Daniel Lafitte, Leah M. Miller, Ruth H. Angeletti, Susan Band Horwitz, Diane Braguer

Journal:

Analytical Biochemistry

Year:

2009

Language:

english

File:

PDF, 499 KB

english, 2009

13

Curacin D, aN antimitotic agent from the marine Cyanobacterium Lyngbya majuscula

Brian Márquez, Pascal Verdier-Pinard, Ernest Hamel, William H. Gerwick

Journal:

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

14

Synthesis and biological evaluation of aryl azide derivatives of combretastatin a-4 as molecular probes for tubulin

Kevin G Pinney, Maria P Mejia, Victor M Villalobos, Brent E Rosenquist, George R Pettit, Pascal Verdier-Pinard, Ernest Hamel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 314 KB

english, 2000

15

Antitumor agents—CLXXV. Anti-tubulin action of (+)-thiocolchicine prepared by partial synthesis

Qian Shi, Pascal Verdier-Pinard, Arnold Brossi, Ernest Hamel, Kuo-Hsiung Lee

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 471 KB

english, 1997

16

Antifungal and cancer cell growth inhibitory activities of 1-(3′,4′,5′-trimethoxyphenyl)-2-nitro-ethylene

R. K. Pettit, E. Hamel, P. Verdier-Pinard, R. W. Roberson, K. C. Hazen, G. R. Pettit, Laura C. Crews

Journal:

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

17

Differential in vitro action of S-12363, a new vinblastine derivative, and of its epimer on microtubule proteins

Michel Wright, Michèle Garès, Pascal Verdier-Pinard, André Moisand, Maryse Berlion, Jean Jacques Legrand, Jean Pierre Bizzari

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.41 MB

english, 1991

18

Microtubule targeting agents: from biophysics to proteomics

D. Calligaris, P. Verdier-Pinard, F. Devred, C. Villard, D. Braguer, Daniel Lafitte

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 569 KB

english, 2010

19

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

Lakshmanan, Viswanathan, Bray, Patrick G, Verdier-Pinard, Dominik, Johnson, David J, Horrocks, Paul, Muhle, Rebecca A, Alakpa, George E, Hughes, Ruth H, Ward, Steve A, Krogstad, Donald J

Journal:

The EMBO Journal

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

20

Mechanisms of Taxol resistance related to microtubules

Orr, George A, Verdier-Pinard, Pascal, McDaid, Hayley, Horwitz, Susan Band

Journal:

Year:

2003

Language:

english

File:

PDF, 369 KB

english, 2003

21

Characterization of a human βV-tubulin antibody and expression of this isotype in normal and malignant human tissue

Suzan K. Chao, Yihong Wang, Pascal Verdier-Pinard, Chia-Ping H. Yang, Lingling Liu, Alicia Rodriguez-Gabin, Hayley M. McDaid, Susan Band Horwitz

Journal:

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

22

Neurotrophins alter the numbers of neurotransmitter-ir mature vagal/glossopharyngeal visceral afferent neurons in vitro

Cinda J. Helke, Dominik Verdier-Pinard

Journal:

Year:

2000

Language:

english

File:

PDF, 382 KB

english, 2000

23

A Novel Palladium-Mediated Coupling Approach to 2,3-Disubstituted Benzo[b]thiophenes and Its Application to the Synthesis of Tubulin Binding Agents

Flynn, Bernard L., Verdier-Pinard, Pascal, Hamel, Ernest

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 134 KB

english, 2001

24

Biosynthesis of Radiolabeled Curacin A and Its Rapid and Apparently Irreversible Binding to the Colchicine Site of Tubulin

Pascal Verdier-Pinard, Namthip Sitachitta, James V Rossi, Dan L Sackett, William H Gerwick, Ernest Hamel

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 86 KB

english, 1999

25

Tyrosine-dependent capture of CAP-Gly domain‐containing proteins in complex mixture by EB1 C-terminal peptidic probes

David Calligaris, Cristina Manatschal, Marlène Marcellin, Claude Villard, Bernard Monsarrat, Odile Burlet-Schiltz, Michel O. Steinmetz, Diane Braguer, Daniel Lafitte, Pascal Verdier-Pinard

Journal:

Journal of Proteomics

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

26

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry †

Verdier-Pinard, Pascal, Wang, Fang, Burd, Berta, Angeletti, Ruth Hogue, Horwitz, Susan Band, Orr, George A.

Journal:

Year:

2003

Language:

english

File:

PDF, 159 KB

english, 2003

27

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals

Pascal Verdier-Pinard, Michèle Garès, Michel Wright

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 494 KB

english, 1999

28

646 POSTER Insights into the mechanism of microtubule stabilization by Taxol

H. Xiao, P. verdier-pinard, N. Fernandez-Fuentes, R. Angeletti, A. Fiser, G. Orr, S. Band Horwitz

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

29

Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression

Diana Connolly, Zhixia Yang, Maria Castaldi, Nichelle Simmons, Maja H Oktay, Salvatore Coniglio, Melissa J Fazzari, Pascal Verdier-Pinard, Cristina Montagna

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.93 MB

english, 2011

30

Antineoplastic Agents. 379. Synthesis of Phenstatin Phosphate 1a,†

Pettit, George R., Toki, Brian, Herald, Delbert L., Verdier-Pinard, Pascal, Boyd, Michael R., Hamel, Ernest, Pettit, Robin K.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998

31

Distinct Pose of Discodermolide in Taxol Binding Pocket Drives a Complementary Mode of Microtubule Stabilization

Khrapunovich-Baine, Marina, Menon, Vilas, Verdier-Pinard, Pascal, Smith, Amos B., Angeletti, Ruth Hogue, Fiser, Andras, Horwitz, Susan Band, Xiao, Hui

Journal:

Year:

2009

Language:

english

File:

PDF, 4.81 MB

english, 2009

32

Antitumor Agents. 172. Synthesis and Biological Evaluation of Novel Deacetamidothiocolchicin-7-ols and Ester Analogs as Antitubulin Agents †

Shi, Qian, Verdier-Pinard, Pascal, Brossi, Arnold, Hamel, Ernest, McPhail, Andrew T., Lee, Kuo-Hsiung

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 439 KB

english, 1997

33

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites

Honore, S., Pagano, A., Gauthier, G., Bourgarel-Rey, V., Verdier-Pinard, P., Civiletti, K., Kruczynski, A., Braguer, D.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 677 KB

english, 2008

34

Analysis of Tubulin Isotypes and Mutations from Taxol-Resistant Cells by Combined Isoelectrofocusing and Mass Spectrometry †

Verdier-Pinard, Pascal, Wang, Fang, Martello, Laura, Burd, Berta, Orr, George A., Horwitz, Susan Band

Journal:

Year:

2003

Language:

english

File:

PDF, 146 KB

english, 2003

35

Detection of Human βV-Tubulin Expression in Epithelial Cancer Cell Lines by Tubulin Proteomics †

Verdier-Pinard, Pascal, Shahabi, Shohreh, Wang, Fang, Burd, Berta, Xiao, Hui, Goldberg, Gary L., Orr, George A., Horwitz, Susan Band

Journal:

Year:

2005

Language:

english

File:

PDF, 803 KB

english, 2005

36

Design, Synthesis, and Biological Evaluation of a Series of Lavendustin A Analogues That Inhibit EGFR and Syk Tyrosine Kinases, as Well as Tubulin Polymerization

Mu, Fanrong, Coffing, Stephanie L., Riese, David J., Geahlen, Robert L., Verdier-Pinard, Pascal, Hamel, Ernest, Johnson, Jill, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

37

Post-Translational Modifications to Toxoplasma gondii α- and β-Tubulins Include Novel C-Terminal Methylation

Xiao, Hui, El Bissati, Kamal, Verdier-Pinard, Pascal, Burd, Berta, Zhang, Hongshan, Kim, Kami, Fiser, Andras, Angeletti, Ruth Hogue, Weiss, Louis M.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 4.51 MB

english, 2010

38

Increased Levels of a Unique Post-Translationally Modified βIVb-Tubulin Isotype in Liver Cancer †

Miller, Leah M., Menthena, Anuradha, Chatterjee, Champak, Verdier-Pinard, Pascal, Novikoff, Phyllis M., Horwitz, Susan Band, Angeletti, Ruth Hogue

Journal:

Year:

2008

Language:

english

File:

PDF, 2.17 MB

english, 2008

39

Antitumor Agents. 183. † Syntheses, Conformational Analyses, and Antitubulin Activity of Allothiocolchicinoids

Shi, Qian, Chen, Ke, Chen, Xin, Brossi, Arnold, Verdier-Pinard, Pascal, Hamel, Ernest, McPhail, Andrew T., Tropsha, Alexander, Lee, Kuo-Hsiung

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

40

Structure and Absolute Stereochemistry of Hectochlorin, a Potent Stimulator of Actin Assembly

Marquez, Brian L., Watts, Karl Shawn, Yokochi, Alexandre, Roberts, Mary Ann, Verdier-Pinard, Pascal, Jimenez, Jorge I., Hamel, Ernest, Scheuer, Paul J., Gerwick, William H.

Journal:

Journal of Natural Products

Year:

2002

Language:

english

File:

PDF, 728 KB

english, 2002

41

MALDI In-Source Decay of High Mass Protein Isoforms: Application to α- and β-Tubulin Variants

Calligaris, David, Villard, Claude, Terras, Lionel, Braguer, Diane, Verdier-Pinard, Pascal, Lafitte, Daniel

Journal:

Analytical Chemistry

Year:

2010

Language:

english

File:

PDF, 3.13 MB

english, 2010

42

Convergent synthesis and preliminary biological evaluation of (±)-B-norrhazinal †

Banwell, Martin, Edwards, Alison, Smith, Jason, Hamel, Ernest, Verdier-Pinard, Pascal

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 107 KB

english, 2000

43

Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

Banwell, Martin G., Edwards, Alison J., Jolliffe, Katrina A., Smith, Jason A., Hamel, Ernest, Verdier-Pinard, Pascal

Journal:

Organic & Biomolecular Chemistry

Year:

2003

Language:

english

File:

PDF, 270 KB

english, 2003

44

Septin roles in tumorigenesis

Connolly, Diana, Abdesselam, Ines, Verdier-Pinard, Pascal, Montagna, Cristina

Journal:

Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.40 MB

english, 2011

45

Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin

Dabydeen, D. A., Burnett, J. C., Bai, R., Verdier-Pinard, P., Hickford, S. J. H., Pettit, G. R., Blunt, J. W., Munro, M. H. G., Gussio, R., Hamel, E.

Journal:

Molecular Pharmacology

Year:

2006

Language:

english

File:

PDF, 746 KB

english, 2006

46

Antitumor Agents. 192. Antitubulin Effect and Cytotoxicity of C(7)-Oxygenated Allocolchicinoids

Guan, Jian, Zhu, Xiao-Kang, Brossi, Arnold, Tachibana, Yoko, Bastow, Kenneth F., Verdier-Pinard, Pascal, Hamel, Ernest, McPhail, Andrew T., Lee, Kuo-Hsiung

Journal:

Collection of Czechoslovak Chemical Communications

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

47

Insights into the mechanism of microtubule stabilization by Taxol

Xiao, H., Verdier-Pinard, P., Fernandez-Fuentes, N., Burd, B., Angeletti, R., Fiser, A., Horwitz, S. B., Orr, G. A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 4.07 MB

english, 2006

48

Chloroquine Resistance Modulated in Vitro by Expression Levels of the Plasmodium falciparum Chloroquine Resistance Transporter

Waller, K. L., Muhle, R. A., Ursos, L. M., Horrocks, P., Verdier-Pinard, D., Sidhu, A. B. S., Fujioka, H., Roepe, P. D., Fidock, D. A.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 433 KB

english, 2003

49

The clinical development of new mitotic inhibitors that stabilize the microtubule

Mani, Sridhar, Macapinlac, Manuel, Goel, Sanjay, Verdier-Pinard, Dominik, Fojo, Tito, Rothenberg, Mace, Colevas, Dimitrios

Journal:

Anti-Cancer Drugs

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

50

Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments

Verdier-Pinard, P., Salaun, D., Bouguenina, H., Shimada, S., Pophillat, M., Audebert, S., Agavnian, E., Coslet, S., Charafe-Jauffret, E., Tachibana, T., Badache, A.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.98 MB

english, 2017